The importance of avoiding AGEs (Advanced Glycation End Products) to prevent aging

Humans are creatures that age if they live long enough. For exampleAs you get older, you become more susceptible to the following diseases.

There is always a reason why the human body ages.
Aging doesn't occur because the human body naturally deteriorates; rather, it's because some kind of change takes place in the tissues within the body..theSubstances that have recently begun to attract attention as common triggers for agingThere is.

AGEs (Advanced Glycation End Products) accelerate aging.

In all of the aforementioned diseases 1 through 7, the substance that is deeply involved in the progression of human aging is a substance in which proteins and sugars are stuck together and cannot be separated."AGEs (Advanced Glycation End Products)"*is.

＊ AGEs, Ages= This is a substance that turns brown when sugar and protein are heated together; for example, the brown part on the surface of a cake made by mixing flour (sugar) and eggs (protein).

The binding of protein and sugar"Saccharification"This is called glycation, a phenomenon that generates AGEs in the body.

As AGEs accumulate in the body over time during one's lifetime, it increases susceptibility to the diseases listed in points 1 through 7 above.

theCollagen (protein) is the first to be affected by AGEs (glycation). (In other words,Aging is largely caused by the glycation of collagen. ). Unless this is prevented, applying lotions and serums won't be very effective.

The mechanism by which AGEs are produced in the body

theReaction equation that produces AGEs (Advanced Glycation End Products), which cause aging.The following are examples:

(Protein + Sugar) × Time = AGEs (Advanced Glycation End Products) ⇒ Aging

・Blood glucose level × duration = amount of AGEsThat's also a valid point.

The mechanism is as follows:

therefore,High blood sugar levels accelerate the glycation reaction, which in turn accelerates aging.That's right.

Let's look at an example. When you have diabetes, the glycation reaction progresses more easily than in healthy individuals.

This happened because,Now that the substances that cause aging (AGEs) have been discovered, the solution is to remove or reduce them.That's the reason.

Therefore,One way to stay youthful and healthy is to minimize the accumulation of AGEs (Advanced Glycation End Products).Yes. Also,By restricting carbohydrate intake, you can reduce the production of endogenous AGEs (i.e., AGEs produced within the body), thus helping to curb the accumulation of AGEs. That's one of the reasons why carbohydrate restriction is so popular.

Furthermore, by avoiding the consumption of foods containing excessive amounts of carbohydrates (to prevent a rapid increase in blood sugar levels), you can avoid the formation of endogenous AGEs.

Regarding the generation of AGEs,The true nature of AGEs (Advanced Glycation End Products) and how they are formed. Please also refer to the following.

AGEs are also found in food.

however,AGEs contained in food are also absorbed into the body at a rate of about 7% through food intake (i.e., meals).Research has revealed this to be the case.Exogenous AGEs (= diet)to doAnd there is the intake of AGEs contained in food.That's the point.

Those who want to stay youthful and healthy forever should take steps to suppress the accumulation of AGEs (Advanced Glycation End Products) in their bodies.Restricting carbohydrate intake can suppress endogenous AGEs (Advanced Glycation End Products), which are produced in the body when sugar combines with proteins after consuming carbohydrates.Of course, Avoid consuming foods that contain large amounts of AGEs, and inhibit the absorption of exogenous AGEs (AGEs contained in the food itself) into the body.This is recommended.

theAGEs (Advanced Glycation End Products = brown substances formed when sugars and proteins are heated)It is found in many of the following foods.

• Grilled meat or fish (especially the brown, burnt parts)
• cake
• Caramel, rice crackers, snack foods (especially potato chips, french fries, etc.)

Not only carbohydrate restriction,Avoiding these foods as much as possible is important for maintaining youthfulness and good health throughout your life.。

Professor Yamagishi of Kurume University in Kyushu (one of the leading experts on AGEs) provides a clear explanation of exogenous AGEs (AGEs ingested through food). He uses grilled meat and hamburgers as examples to warn against consuming such foods.

Professor Yamagishi has also appeared on Thai television programs. This may be surprising to Japanese people,Thailand is known as a country with a very high level of medical care.Therefore, this kind of TV program might be broadcast.

Books related to AGEs

The following books explain the theoretical aspects of AGEs. They are recommended for those who want to thoroughly study the theory.