Anti-aging

Glycation is one of the factors contributing to aging. Does the accumulation of AGEs due to glycation shorten lifespan?

Anti-aging
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When high blood sugar levels persist, the body accumulates substances that accelerate aging.AGEs (Advanced Glycation End Products)This will be generated.SaccharificationIt is called that.For example, one of the causes of dull skin, blemishes, and wrinkles is the accumulation of AGEs (Advanced Glycation End Products) due to glycation.

Quoted and adapted by the author from "The Science of Rejuvenation: True Anti-Aging Proven by Medicine" by Koichiro Fujita.

The manga above is an excerpt from "The Science of Rejuvenation: True Anti-Aging Proven by Medicine." For more information, please see below.You can read a sample via the Amazon link below ↓

That's why adopting lifestyle habits that minimize the accumulation of AGEs (Advanced Glycation End Products) due to glycation is extremely important. Doing so will not only improve your skin, but it can also help you live longer.

This article discusses the causes of agingSaccharificationI will explain this in detail.This article will cover the mechanisms by which glycation occurs and the health problems it can cause.

Incidentally, there are many other problems caused by high blood sugar besides glycation. Please refer to the following article for more information.

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Why do AGEs (Advanced Glycation End Products) accumulate?

For example, eating rice raises your blood sugar levels.

Of those, the ones that couldn't be processed and were left overCarbohydratesHowever, it binds to proteins in the body (such as those in the skin, blood vessels, and bones), producing AGEs (Advanced Glycation End Products).ThisSaccharificationThis process is called the Maillard reaction, named after the French physicist Louis-Camille Merhar who discovered it.

for example,Before baking, the cookies are white and soft,When baked, it turns brown and hard.That's right. Actually, this tooSaccharificationThat's right. The sugar in cookies binds with proteins in eggs and milk, causing them to denature.

You can see that the brown color deepens as the sugar concentration increases ↓

In the case of food, it's actually a good thing because it becomes nicely browned and delicious. However, when this happens inside the body, it becomes a major problem.

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When skin undergoes glycation, wrinkles form and it becomes dull and brownish.

For example, collagen in the skin is made of protein. When collagen in the skin combines with sugar and undergoes glycation, the collagen fibers are destroyed.

When collagen fibers are destroyed,The skin loses its firmness., and it also loses its elasticity.It will sag..moreover,Wrinkles will also form.Furthermore, just as cookies bake to a golden brown,Your skin will also become dull and brownish.

Those who regularly consume sweet snacks or juices containing a lot of sweeteners should be careful.

Since hair is made of protein, glycation can cause it to lose its elasticity and shine.

*For more detailed information, please refer to the link below ↓
Skin Glycation Stress and Photoaging Masamitsu Ichihashi, Masayuki Yagi, Keitaro Nomoto, Yoshikazu Yonei Glycation Stress Research Center, Anti-Aging Research Center, Graduate School of Biomedical Sciences, Doshisha Universityhttp://anti-aging.gr.jp/english/pdf/2011/8(3)2329J.pdf

As glycation progresses, lifespan shortens.

Furthermore, blood vessels and internal organs are also made of protein. Every part of the body is made of protein.

When cookies are baked, a glycation reaction occurs, causing them to harden.That's what I explained, right?

When glycation occurs in blood vessels, they harden in a similar way.

AGE Makita ClinicWhat is AGE?Quoted from and modified by the author from "[Title of the book]".

Commonly known as,arteriosclerosisIt will causeAs arteriosclerosis progresses,Myocardial infarction and stroke, which carry a high risk of death.This becomes more likely to happen. Furthermore, and this is even more frightening,

Once something has been glycated, it almost never returns to its original state.

It's the same principle as how baked cookies can't return to their original white, soft dough state.

I think this story alone should give you an idea of just how dangerous glycation can be.

The key to longevity lies in preventing glycation from an early stage and avoiding the accumulation of AGEs, which are substances that accelerate aging.

To achieve this, first and foremost, it is effective to maintain appropriate blood sugar levels.

AGEs sensor - a device for measuring the amount of AGEs accumulated in the body -

We now understand that it's "dangerous" when AGEs accumulate in the body, but I think most people don't know how much AGEs they currently have.

Surprisingly, there is a device that can determine the amount of AGEs (Advanced Glycation End Products) accumulated in your own body.

It's called the "AGEs Sensor - Advanced Glycation End Products Measurement Device." Since this is a product for medical institutions, you probably can't buy it normally, so it's best to find a hospital that performs this test.

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